Journal article icon

Journal article

The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons.

Abstract:

Cortical interneurons in rodents are generated in the ventral telencephalon and migrate tangentially into the cortex. This process requires the coordinated action of many intrinsic and extrinsic factors. Here we show that Robo1 and Robo2 receptor proteins are dynamically expressed throughout the period of corticogenesis and colocalize with interneuronal markers, suggesting that they play a role in the migration of these cells. Analysis of Robo mutants showed a marked increase in the number of...

Expand abstract

Actions


Access Document


Publisher copy:
10.1016/j.ydbio.2007.10.052

Authors


Expand authors...
Journal:
Developmental biology
Volume:
313
Issue:
2
Pages:
648-658
Publication date:
2008-01-05
DOI:
EISSN:
1095-564X
ISSN:
0012-1606
URN:
uuid:d3994a35-c530-46df-bfea-7eef7af2b2a2
Source identifiers:
324263
Local pid:
pubs:324263

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP