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Journal article

Transcriptional profiling of synovial macrophages using minimally invasive ultrasound-guided synovial biopsies in rheumatoid arthritis

Abstract:
Objective Currently, there are no reliable biomarkers for predicting therapeutic response in patients with rheumatoid arthritis (RA). The synovium may unlock critical information for determining efficacy as reduction in numbers of sublining synovial macrophages remains the most reproducible biomarker. Thus, a clinically actionable method for collection of synovial tissue, which can be analyzed using high-throughput strategies, must become a reality. Methods ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1002/art.40453

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS; KIR
Role:
Author
Publisher:
John Wiley and Sons Ltd Publisher's website
Journal:
Arthritis and Rheumatology Journal website
Volume:
70
Issue:
6
Pages:
841-854
Publication date:
2018-05-03
Acceptance date:
2018-02-21
DOI:
ISSN:
2326-5205
Pubs id:
pubs:826674
URN:
uri:d394c528-b4b3-48ac-9bd5-761770394075
UUID:
uuid:d394c528-b4b3-48ac-9bd5-761770394075
Local pid:
pubs:826674

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