- Abstract:
-
Infectious pathogens have long been recognized as potentially powerful agents impacting on the evolution of human genetic diversity. Analysis of large-scale case-control studies provides one of the most direct means of identifying human genetic variants that currently impact on susceptibility to particular infectious diseases. For over 50 years candidate gene studies have been used to identify loci for many major causes of human infectious mortality, including malaria, tuberculosis, human imm...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1098/rstb.2011.0275
-
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- Journal:
- Philosophical transactions of the Royal Society of London. Series B, Biological sciences
- Volume:
- 367
- Issue:
- 1590
- Pages:
- 840-849
- Publication date:
- 2012-03-05
- DOI:
- EISSN:
-
1471-2970
- ISSN:
-
0962-8436
- URN:
-
uuid:d38c440f-6e29-4d44-8074-cf1a8546da19
- Source identifiers:
-
254261
- Local pid:
- pubs:254261
- Copyright date:
- 2012
Journal article
Evolution, revolution and heresy in the genetics of infectious disease susceptibility.
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