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Sulfonylurea inadequacy: efficacy of addition of insulin over 6 years in patients with type 2 diabetes in the U.K. Prospective Diabetes Study (UKPDS 57).

Abstract:

OBJECTIVE: To evaluate the efficacy of the addition of insulin when maximal sulfonylurea therapy is inadequate in individuals with type 2 diabetes. RESEARCH DESIGN AND METHODS: Glycemic control, hypoglycemia, and body weight were monitored over 6 years in 826 patients with newly diagnosed type 2 diabetes in 8 of 23 U.K. Prospective Diabetes Study (UKPDS) centers that used a modified protocol. Patients were randomly allocated to a conventional glucose control policy, primarily with diet (n = ...

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Publication status:
Published

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Publisher copy:
10.2337/diacare.25.2.330

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
Role:
Author
Journal:
Diabetes care
Volume:
25
Issue:
2
Pages:
330-336
Publication date:
2002-02-05
DOI:
EISSN:
1935-5548
ISSN:
0149-5992
URN:
uuid:d3806596-5cb0-486f-a2ce-277096cb58cf
Source identifiers:
15153
Local pid:
pubs:15153

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