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Phosphate wasting disorders in adults

Abstract:

A cause of hypophosphatemia is phosphate wasting disorders. Knowledge concerning mechanisms involved in phosphate wasting disorders has greatly increased in the last decade by the identification of phosphatonins, among them FGF-23. FGF-23 is a primarily bone derived factor decreasing renal tubular reabsorption of phosphate and the synthesis of calcitriol. Currently, pharmacological treatment of these disorders offers limited efficacy and is potentially associated to gastrointestinal, renal an...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1007/s00198-018-4618-2

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Subgroup:
Botnar Research Centre
Oxford college:
Somerville College
Role:
Author
ORCID:
0000-0001-7985-0048
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Fondazione Italiana Ricerca Malattie Ossee More from this funder
Publisher:
Springer Verlag Publisher's website
Journal:
Osteoporosis International Journal website
Volume:
29
Issue:
11
Pages:
2369–2387
Publication date:
2018-07-16
Acceptance date:
2018-06-19
DOI:
EISSN:
1433-2965
ISSN:
0937-941X
Pubs id:
pubs:890375
URN:
uri:d357335b-3236-4830-a1d2-7d0f1fb1e673
UUID:
uuid:d357335b-3236-4830-a1d2-7d0f1fb1e673
Local pid:
pubs:890375

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