Journal article
Causes and consequences of chromatin variation between inbred mice
- Abstract:
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Variation at regulatory elements, identified through hypersensitivity to digestion by DNase I, is believed to contribute to variation in complex traits, but the extent and consequences of this variation are poorly characterized. Analysis of terminally differentiated erythroblasts in eight inbred strains of mice identified reproducible variation at approximately 6% of DNase I hypersensitive sites (DHS). Only 30% of such variable DHS contain a sequence variant predictive of site variation. Neve...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1.1MB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pgen.1003570
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Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PLoS Genetics More from this journal
- Volume:
- 9
- Issue:
- 6
- Pages:
- e1003570
- Publication date:
- 2013-06-13
- Acceptance date:
- 2013-05-02
- DOI:
- EISSN:
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1553-7404
- ISSN:
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1553-7390
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:407704
- UUID:
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uuid:d33591b4-cdb8-452c-98f0-066565987dd4
- Local pid:
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pubs:407704
- Source identifiers:
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407704
- Deposit date:
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2013-11-16
Terms of use
- Copyright holder:
- Hosseini et al
- Copyright date:
- 2013
- Notes:
- © 2013 Hosseini et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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