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Identification of the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1.

Abstract:

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterised by tumours of the parathyroids, pancreas and anterior pituitary that represents one of the familial cancer syndromes. The MEN1 locus has been previously localised to chromosome 11q13, and a <300 kb gene-rich region flanked centromerically by PYGM and telomerically by D11S1783 defined by combined meiotic and tumour deletion mapping studies. Two candidate genes, ZFM1 and PPP2R5B, from this region have ...

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Publisher copy:
10.1093/hmg/6.7.1177

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Journal:
Human molecular genetics
Volume:
6
Issue:
7
Pages:
1177-1183
Publication date:
1997-07-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:d3316a50-d9fa-4113-a584-2d2316a44775
Source identifiers:
106
Local pid:
pubs:106

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