Thesis
The interaction between the Marek’s Disease Virus (MDV) neurovirulence factor pp14 and the host transcription factor, CREB3
- Abstract:
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Marek’s Disease Virus (MDV) induces a wide range of neurological syndromes in susceptible hosts; however, the mechanisms behind the MDV-induced neuropathology are still poorly understood. The immediate-early 14kDa phosphoprotein, pp14, is associated with the neurovirulence phenotype of the virus. Yeast-two-hybrid screening identified the ER-bound transcription regulator, human CREB3 (cAMP Response Element-Binding protein), as an interacting partner of pp14, and fluorescence colocalisation ...
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Authors
Contributors
+ Grimes, J
Role:
Supervisor
+ Owens, R
Role:
Supervisor
+ Nair, V
Role:
Supervisor
Funding
Biotechnology and Biological Sciences Research Council
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The Pirbright Institute
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University of Oxford
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Subjects:
- UUID:
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uuid:d2fc6bd4-bc3a-4a37-924b-86881096a9b5
- Deposit date:
- 2018-06-10
Terms of use
- Copyright holder:
- Sabaratnam, K
- Copyright date:
- 2017
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