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Journal article

Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene.

Abstract:

BACKGROUND: There is a need to develop robust and clinically applicable gene expression signatures. Hypoxia is a key factor promoting solid tumour progression and resistance to therapy; a hypoxia signature has the potential to be not only prognostic but also to predict benefit from particular interventions. METHODS: An approach for deriving signatures that combine knowledge of gene function and analysis of in vivo co-expression patterns was used to define a common hypoxia signature from thre...

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Publication status:
Published

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Publisher copy:
10.1038/sj.bjc.6605450
Journal:
British journal of cancer More from this journal
Volume:
102
Issue:
2
Pages:
428-435
Publication date:
2010-01-01
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
Language:
English
Keywords:
Pubs id:
pubs:125256
UUID:
uuid:d2e4d089-8737-4894-b910-886dd03a889c
Local pid:
pubs:125256
Source identifiers:
125256
Deposit date:
2012-12-19

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