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Journal article

Incorporating local Ca2+ dynamics into single cell ventricular models

Abstract:

Understanding physiological mechanisms underlying the activity of the heart is of great medical importance. Mathematical modeling and numerical simulation have become a widely accepted method of unraveling the underlying mechanism of the heart. Calcium (Ca2∈+∈) dynamics regulate the excitation-contraction coupling in heart muscle cells and hence are among the key players in maintaining normal activity of the heart. Many existing ventricular single cell models lack the biophysically detailed d...

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Publication status:
Published

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Journal:
COMPUTATIONAL SCIENCE - ICCS 2008, PT 1 More from this journal
Volume:
5101
Issue:
PART 1
Pages:
66-75
Publication date:
2008-01-01
DOI:
EISSN:
1611-3349
ISSN:
0302-9743
Language:
English
Keywords:
Pubs id:
pubs:238956
UUID:
uuid:d2e37260-5758-4090-8a36-8a3c8b6a6574
Local pid:
pubs:238956
Source identifiers:
238956
Deposit date:
2013-11-16

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