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A model for CD2/CD58-mediated adhesion strengthening.

Abstract:

Stable cell adhesion is vital for structural integrity and functional efficacy. Yet how low affinity adhesion molecules such as CD2 and CD58 can produce stable cell adhesion is still not completely understood. In this paper, we present a theoretical model that simulates the accumulation of CD2 and CD58 in the contact area of a Jurkat T lymphoblast and a CD58-containing substrate. The cell is assumed to have a spherical shape initially and it is allowed to spread gradually on a circular substr...

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Publisher copy:
10.1007/s10439-005-2504-5

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Annals of biomedical engineering More from this journal
Volume:
33
Issue:
4
Pages:
483-493
Publication date:
2005-04-01
DOI:
EISSN:
1573-9686
ISSN:
0090-6964
Language:
English
Keywords:
Pubs id:
pubs:482622
UUID:
uuid:d2d867a0-3106-4cd3-b89c-bc070bf70efc
Local pid:
pubs:482622
Source identifiers:
482622
Deposit date:
2014-09-14

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