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The natural history of chronic airflow obstruction.

Abstract:

A prospective epidemiological study of the early stages of the development of chronic obstructive pulmonary disease was performed on London working men. The findings showed that forced expiratory volume in one second (FEV1) falls gradually over a lifetime, but in most non-smokers and many smokers clinically significant airflow obstruction never develops. In susceptible people, however, smoking causes irreversible obstructive changes. If a susceptible smoker stops smoking he will not recover h...

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Publication status:
Published

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Publisher copy:
10.1136/bmj.1.6077.1645

Authors


Fletcher, C More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Journal:
British medical journal
Volume:
1
Issue:
6077
Pages:
1645-1648
Publication date:
1977-06-05
DOI:
EISSN:
1468-5833
ISSN:
0007-1447
URN:
uuid:d2c41819-8f2f-4c3e-aa92-3b90756e99eb
Source identifiers:
79678
Local pid:
pubs:79678

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