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GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014.

Abstract:

G-protein coupled receptors (GPCRs) are the targets of over half of all prescribed drugs today. The UniProt database has records for about 800 proteins classified as GPCRs, but drugs have only been developed against 50 of these. Thus, there is huge potential in terms of the number of targets for new therapies to be designed. Several breakthroughs in GPCRs biased pharmacology, structural biology, modelling and scoring have resulted in a resurgence of interest in GPCRs as drug targets. Therefor...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher:
Springer Berlin Heidelberg
Journal:
Naunyn-Schmiedeberg's Archives of Pharmacology More from this journal
Volume:
388
Issue:
8
Pages:
883-903
Publication date:
2015-08-01
DOI:
EISSN:
1432-1912
ISSN:
0028-1298
Language:
English
Pubs id:
pubs:513047
UUID:
uuid:d2c3aacf-3650-4311-b849-751da3be3576
Local pid:
pubs:513047
Source identifiers:
513047
Deposit date:
2015-06-30

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