A genome-wide association search for type 2 diabetes genes in African Americans.

Palmer, N; McDonough, C; Hicks, P; Roh, B; Wing, MR; An, S; Hester, J; Cooke, J; Bostrom, M; Rudock, M; Talbert, M; Lewis, J; Ferrara, A; Lu, L; Ziegler, J; Sale, M; Divers, J; Shriner, D; Adeyemo, A; Rotimi, C; Ng, M; Langefeld, C; Freedman, B; Bowden, D; Voight, B; Scott, L; Steinthorsdottir, V; Morris, A; Dina, C; Welch, R; Zeggini, E; Huth, C; Aulchenko, Y; Thorleifsson, G; McCulloch, L; Ferreira, T; Grallert, H; Amin, N; Wu, G; Willer, C; Raychaudhuri, S; McCarroll, SA; Langenberg, C; Hofmann, O; Dupuis, J; Qi, L; Segre, A; van Hoek, M; Navarro, P; Ardlie, K; Balkau, B; Benediktsson, R; Bennett, A; Blagieva, R; Boerwinkle, E; Bonnycastle, L; Bostrom, K; Bravenboer, B; Bumpstead, S; Burtt, N; Charpentier, G; Chines, P; Cornelis, M; Couper, D; Crawford, G; Doney, A; Elliott, K; Elliott, A; Erdos, MR; Fox, C; Franklin, C; Ganser, M; Gieger, C; Grarup, N; Green, T; Griffin, S; Groves, C; Guiducci, C; Hadjadj, S; Hassanali, N; Herder, C; Isomaa, B; Jackson, A; Johnson, P; Jorgensen, T; Kao, W; Klopp, N; Kong, A; Kraft, P; Kuusisto, J; Lauritzen, T; Li, M; Lieverse, A; Lindgren, C; Lyssenko, V; Marre, M; Meitinger, T; Midthjell, K; Morken, M; Narisu, N; Nilsson, P; Owen, K; Payne, F; Perry, JR; Petersen, A; Platou, C; Proenca, C; Prokopenko, I; Rathmann, W; Rayner, N; Robertson, N; Rocheleau, G; Roden, M; Sampson, M; Saxena, R; Shields, B; Shrader, P; Sigurdsson, G; Sparso, T; Strassburger, K; Stringham, H; Sun, Q; Swift, A; Thorand, B; Tichet, J; Tuomi, T; van Dam, R; van Haeften, T; van Herpt, T; van Vliet-Ostaptchouk, J; Walters, G; Weedon, M; Wijmenga, C; Witteman, J; Bergman, R; Cauchi, S; Collins, F; Gloyn, A; Gyllensten, U; Hansen, T; Hide, W; Hitman, G; Hofman, A; Hunter, D; Hveem, K; Laakso, M; Mohlke, K; Morris, A; Palmer, C; Pramstaller, P; Rudan, I; Sijbrands, E; Stein, L; Tuomilehto, J; Uitterlinden, A; Walker, M; Wareham, N; Watanabe, R; Abecasis, G; Boehm, B; Campbell, H; Daly, M; Hattersley, A; Hu, F; Meigs, J; Pankow, J; Pedersen, O; Wichmann, H; Barroso, I; Florez, J; Frayling, T; Groop, L; Sladek, R; Thorsteinsdottir, U; Wilson, J; Illig, T; Froguel, P; van Duijn, C; Stefansson, K; Altshuler, D; Boehnke, M; McCarthy, M; Soranzo, N; Wheeler, E; Glazer, N; Bouatia-Naji, N; Magi, R; Randall, J; Johnson, T; Elliott, P; Rybin, D; Henneman, P; Dehghan, A; Hottenga, J; Song, K; Goel, A; Egan, J; Lajunen, T; Doney, A; Kanoni, S; Cavalcanti-Proenca, C; Kumari, M; Timpson, N; Zabena, C; Ingelsson, E; An, P; O'Connell, J; Luan, J; Elliott, A; McCarroll, SA; Roccasecca, R; Pattou, F; Sethupathy, P; Ariyurek, Y; Barter, P; Beilby, J; Ben-Shlomo, Y; Bergmann, S; Bochud, M; Bonnefond, A; Borch-Johnsen, K; Bottcher, Y; Brunner, E; Bumpstead, S; Chen, Y; Chines, P; Clarke, R; Coin, L; Cooper, M; Crisponi, L; Day, I; de Geus, E; Delplanque, J; Fedson, A; Fischer-Rosinsky, A; Forouhi, N; Frants, R; Franzosi, MG; Galan, P; Goodarzi, M; Graessler, J; Grundy, S; Gwilliam, R; Hallmans, G; Hammond, N; Han, X; Hartikainen, A; Hayward, C; Heath, S; Hercberg, S; Hicks, A; Hillman, DR; Hingorani, A; Hui, J; Hung, J; Jula, A; Kaakinen, M; Kaprio, J; Kesaniemi, Y; Kivimaki, M; Knight, B; Koskinen, S; Kovacs, P; Kyvik, K; Lathrop, G; Lawlor, D; Le Bacquer, O; Lecoeur, C; Li, Y; Mahley, R; Mangino, M; Manning, A; Martinez-Larrad, M; McAteer, J; McPherson, R; Meisinger, C; Melzer, D; Meyre, D; Mitchell, B; Mukherjee, S; Naitza, S; Neville, M; Oostra, B; Orru, M; Pakyz, R; Paolisso, G; Pattaro, C; Pearson, D; Peden, J; Pedersen, N; Perola, M; Pfeiffer, A; Pichler, I; Polasek, O; Posthuma, D; Potter, S; Pouta, A; Province, M; Psaty, B; Rayner, N; Rice, K; Ripatti, S; Rivadeneira, F; Rolandsson, O; Sandbaek, A; Sandhu, M; Sanna, S; Sayer, A; Scheet, P; Seedorf, U; Sharp, S; Shields, B; Sijbrands, E; Silveira, A; Simpson, L; Singleton, A; Smith, N; Sovio, U; Swift, A; Syddall, H; Syvanen, A; Tanaka, T; Tonjes, A; Uitterlinden, A; van Dijk, K; Varma, D; Visvikis-Siest, S; Vitart, V; Vogelzangs, N; Waeber, G; Wagner, P; Walley, A; Ward, K; Watkins, H; Wild, S; Willemsen, G; Witteman, J; Yarnell, J; Zelenika, D; Zethelius, B; Zhai, G; Zhao, J; Zillikens, M; Borecki, I; Loos, R; Meneton, P; Magnusson, P; Nathan, D; Williams, G; Silander, K; Salomaa, V; Smith, G; Bornstein, SR; Schwarz, P; Spranger, J; Karpe, F; Shuldiner, A; Cooper, C; Dedoussis, G; Serrano-Rios, M; Lind, L; Palmer, L; Franks, P; Ebrahim, S; Marmot, M; Kao, W; Pramstaller, P; Wright, A; Stumvoll, M; Hamsten, A; Buchanan, T; Valle, T; Rotter, J; Siscovick, D; Penninx, B; Boomsma, D; Deloukas, P; Spector, T; Ferrucci, L; Cao, A; Scuteri, A; Schlessinger, D; Uda, M; Ruokonen, A; Jarvelin, MR; Waterworth, D; Vollenweider, P; Peltonen, L; Mooser, V; Sladek, R

Journal article

A genome-wide association search for type 2 diabetes genes in African Americans.

Abstract:: African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have examined T2DM using genome-wide association approaches in this ethnicity. The aim of this study was to identify genes associated with T2DM in the African American population. We performed a Genome Wide Association Study (GWAS) using the Affymetrix 6.0 array in 965 African-American cases with T2DM and end-stage renal disease (T2DM-ESRD) and 1029 population-based controls. The most significant SNPs ...
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APA Style

Palmer, N., McDonough, C., Hicks, P., Roh, B., Wing, M. R., An, S., Hester, J., Cooke, J., Bostrom, M., Rudock, M., Talbert, M., Lewis, J., Ferrara, A., Lu, L., Ziegler, J., Sale, M., Divers, J., Shriner, D., Adeyemo, A., … Sladek, R. (2012). A genome-wide association search for type 2 diabetes genes in African Americans. PloS One, 7(1).

MLA Style

Palmer, N., et al. “A Genome-Wide Association Search for Type 2 Diabetes Genes in African Americans.” PloS One, vol. 7, no. 1, Public Library of Science, 2012.

Chicago Style

Palmer, N, C McDonough, P Hicks, B Roh, MR Wing, S An, J Hester, et al. 2012. “A Genome-Wide Association Search for Type 2 Diabetes Genes in African Americans.” PloS One 7 (1).
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Publisher copy:: 10.1371/journal.pone.0029202

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+ Palmer, N More by this author

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+ McDonough, C More by this author

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+ Hicks, P More by this author

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+ Roh, B More by this author

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+ Wing, MR More by this author

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Funding

+ National Institutes of Health More from this funder

+ Center for Inherited Disease Research More from this funder

+ Johns Hopkins University More from this funder

+ General Clinical Research Center of the Wake Forest University School of Medicine More from this funder

Bibliographic Details

Publisher:: Public Library of Science
Journal:: PloS one More from this journal
Volume:: 7
Issue:: 1
Article number:: e29202
Publication date:: 2012-01-04
DOI:: 10.1371/journal.pone.0029202
EISSN:: 1932-6203

Item Description

Language:: English
Keywords:: Case-Control Studies

Cohort Studies

Validation Studies as Topic

Meta-Analysis as Topic

Polymorphism, Single Nucleotide

African Americans

Humans

Genotype

Diabetes Mellitus, Type 2

Adult

Genome-Wide Association Study

Middle Aged

MAGIC Investigators

Genetic Predisposition to Disease

Aged

DIAGRAM Consortium

Female

Male
Pubs id:: pubs:270663
UUID:: uuid:d2ac5e39-ffb6-4d76-b93f-ff4690682998
Local pid:: pubs:270663
Source identifiers:: 270663
Deposit date:: 2012-12-19

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Copyright holder:: Palmer et al
Notes:: This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

Licence:: CC Attribution (CC BY)

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Journal article

A genome-wide association search for type 2 diabetes genes in African Americans.

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