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The search for a human equivalent of the mouse T-locus - negative results from a study of HL-A types in spina bifida.

Abstract:
The spina bifida/anencephaly complex in man in some ways resembles the effects of T-locus mutants in the mouse. To test the hypothesis that these entities are genetically related, HL-A typing was performed in families with multiple cases of central nervous system abnormality. No evidence of linkage was found between HL-A type and the congenital malformation.
Publication status:
Published

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Authors


Bodmer, JG More by this author
Bodmer, WF More by this author
McDevitt, HO More by this author
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Journal:
Tissue antigens
Volume:
5
Issue:
4
Pages:
234-237
Publication date:
1975-05-05
DOI:
EISSN:
1399-0039
ISSN:
0001-2815
URN:
uuid:d2a69647-2641-4fa2-8575-880358f6cea0
Source identifiers:
487536
Local pid:
pubs:487536

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