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Journal article

Vaccine escape recombinants emerge after pneumococcal vaccination in the United States.

Abstract:

The heptavalent pneumococcal conjugate vaccine (PCV7) was introduced in the United States (US) in 2000 and has significantly reduced invasive pneumococcal disease; however, the incidence of nonvaccine serotype invasive disease, particularly due to serotype 19A, has increased. The serotype 19A increase can be explained in part by expansion of a genotype that has been circulating in the US prior to vaccine implementation (and other countries since at least 1990), but also by the emergence of a ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
Journal:
PLoS pathogens
Volume:
3
Issue:
11
Pages:
e168
Publication date:
2007-11-05
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
URN:
uuid:d2a1f6e3-ea07-4f1a-a6e3-ff2369e264e1
Source identifiers:
92685
Local pid:
pubs:92685

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