Journal article
Th17 cells induce a distinct graft rejection response that does not require IL-17A
- Abstract:
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IL-17A-producing helper T (Th17) cells have been implicated in the pathogenesis of autoimmune disease, inflammatory bowel disease and graft rejection, however the mechanisms by which they cause tissue damage remain ill-defined. We examined what damage Th17 cell lines could inflict on allogeneic skin grafts in the absence of other adaptive lymphocytes. CD4 Th17 cell lines were generated from two TCR transgenic mouse strains, A1(M).RAG1 and Marilyn, each monospecific for the male antigen Dby....
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- Publisher copy:
- 10.1111/j.1600-6143.2011.03971.x
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Bibliographic Details
- Journal:
- American Journal of Transplantation
- Volume:
- 12
- Issue:
- 4
- Pages:
- 835-845
- Publication date:
- 2012-04-01
- DOI:
- EISSN:
-
1600-6143
- ISSN:
-
1600-6135
- Source identifiers:
-
325278
Item Description
- Pubs id:
-
pubs:325278
- UUID:
-
uuid:d2a0995d-3b9d-4106-a46d-102a09fd95e7
- Local pid:
- pubs:325278
- Deposit date:
- 2013-02-20
Terms of use
- Copyright date:
- 2012
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