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New semidominant mutations that affect mouse development.

Abstract:

Dominantly acting mutations that produce visible phenotypes are frequently recovered, either during routine maintenance of colonies or from mutagenesis experiments. We have studied 12 dominant mouse mutations that cause a tail dysmorphology, a coat spotting phenotype, or a combination of these. The majority of these mutations act in a semidominant manner with the homozygous state associated with embryonic lethality and a visible phenotype at or before midgestation. The homozygous phenotypes i...

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Publication status:
Published

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Publisher copy:
10.1002/gene.20071

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Journal:
Genesis (New York, N.Y. : 2000) More from this journal
Volume:
40
Issue:
2
Pages:
109-117
Publication date:
2004-10-01
DOI:
EISSN:
1526-968X
ISSN:
1526-954X

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