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Journal article

FOXP3 expression in blood, synovial fluid and synovial tissue during inflammatory arthritis and intra-articular corticosteroid treatment.

Abstract:

OBJECTIVE: To analyse the distribution of FOXP3+CD25+CD4+ regulatory T cells (Treg) in peripheral blood, synovial fluid and tissue of patients with rheumatic disease during relapse and after local treatment. METHODS: FOXP3 expression was assessed by flow cytometry, immunohistochemistry, immunofluorescence and real-time polymerase chain reaction (RT-PCR). The functional suppressive capacity of Treg was analysed after co-culture with effector CD4+CD25- T cells through assessment of proliferati...

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Publication status:
Published

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Publisher copy:
10.1136/ard.2008.100768

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Journal:
Annals of the rheumatic diseases
Volume:
68
Issue:
12
Pages:
1908-1915
Publication date:
2009-12-05
DOI:
EISSN:
1468-2060
ISSN:
0003-4967
URN:
uuid:d28f9f0c-b2b5-41f1-8ff6-cf5b5515b5ff
Source identifiers:
246553
Local pid:
pubs:246553

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