- Abstract:
-
OBJECTIVE: To analyse the distribution of FOXP3+CD25+CD4+ regulatory T cells (Treg) in peripheral blood, synovial fluid and tissue of patients with rheumatic disease during relapse and after local treatment. METHODS: FOXP3 expression was assessed by flow cytometry, immunohistochemistry, immunofluorescence and real-time polymerase chain reaction (RT-PCR). The functional suppressive capacity of Treg was analysed after co-culture with effector CD4+CD25- T cells through assessment of proliferati...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1136/ard.2008.100768
-
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- Journal:
- Annals of the rheumatic diseases
- Volume:
- 68
- Issue:
- 12
- Pages:
- 1908-1915
- Publication date:
- 2009-12-05
- DOI:
- EISSN:
-
1468-2060
- ISSN:
-
0003-4967
- URN:
-
uuid:d28f9f0c-b2b5-41f1-8ff6-cf5b5515b5ff
- Source identifiers:
-
246553
- Local pid:
- pubs:246553
- Language:
- English
- Keywords:
- Copyright date:
- 2009
Journal article
FOXP3 expression in blood, synovial fluid and synovial tissue during inflammatory arthritis and intra-articular corticosteroid treatment.
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