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Heterogeneity in the effect of different ixodid tick species on human natural killer cell activity.

Abstract:

Tick saliva plays a vital role in blood-feeding, including manipulation of the host response to tick infestation. Furthermore, a diverse number of tick-borne pathogens are transmitted to vertebrate hosts via tick saliva, some of which exploit the immunomodulatory activities of their vector's saliva. We report that salivary gland extracts (SGE) derived from Dermacentor reticulatus adult ticks induce a decrease in the natural killer (NK) activity of effector cells obtained from healthy human bl...

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Publication status:
Published

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Authors


Kocáková, P More by this author
Slovák, M More by this author
Sláviková, M More by this author
Fuchsberger, N More by this author
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Journal:
Parasite immunology
Volume:
24
Issue:
1
Pages:
23-28
Publication date:
2002-01-05
DOI:
EISSN:
1365-3024
ISSN:
0141-9838
URN:
uuid:d269ecc1-874a-4f98-a974-2769d31d8db4
Source identifiers:
404189
Local pid:
pubs:404189

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