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Journal article

Phenotype standardization for statin-induced myotoxicity.

Abstract:

Statins are widely used lipid-lowering drugs that are effective in reducing cardiovascular disease risk. Although they are generally well tolerated, they can cause muscle toxicity, which can lead to severe rhabdomyolysis. Research in this area has been hampered to some extent by the lack of standardized nomenclature and phenotypic definitions. We have used numerical and descriptive classifications and developed an algorithm to define statin-related myotoxicity phenotypes, including myalgia, m...

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Publication status:
Published

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Publisher copy:
10.1038/clpt.2014.121

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Journal:
Clinical pharmacology and therapeutics More from this journal
Volume:
96
Issue:
4
Pages:
470-476
Publication date:
2014-10-01
DOI:
EISSN:
1532-6535
ISSN:
0009-9236
Language:
English
Keywords:
Pubs id:
pubs:475817
UUID:
uuid:d24ce20e-4850-4eea-a81a-15f0dd1d0f45
Local pid:
pubs:475817
Source identifiers:
475817
Deposit date:
2014-07-19

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