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MORTALITY BEFORE AND AFTER HIV-INFECTION IN THE COMPLETE UK POPULATION OF HEMOPHILIACS

Abstract:

DURING 1977-91, 6,278 males diagnosed with haemophilia were living in the UK. During 1979-86, 1,227 were infected with the human immunodeficiency virus (HIV-1) as a result of transfusion therapy (median estimated seroconversion date, October 1982). Among 2,448 with severe haemophilia, the annual death rate was stable at 8 per 1,000 during 1977-84; during 1985-92 death rates remained at 8 per 1,000 among HIV-seronegative patients but rose steeply in seropositive patients, reaching 81 per 1,000...

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Publication status:
Published

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Publisher copy:
10.1038/377079a0

Authors


GIANGRANDE, P More by this author
SPOONER, R More by this author
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Journal:
NATURE
Volume:
377
Issue:
6544
Pages:
79-82
Publication date:
1995-09-07
DOI:
ISSN:
0028-0836
URN:
uuid:d2233e84-ecd6-46ff-9b1f-375870721460
Source identifiers:
95334
Local pid:
pubs:95334

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