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Efficient Switches in Biology and Computer Science

Abstract:

Biological systems are adapted to respond quickly to changes in their environment. Signal processing often leads to all-or-none switch-like activation of downstream pathways. Such biological switches are based on molecular interactions that form positive feedback loops. Proper signal processing and switching have to be made by the noisy interactions of fluctuating molecular components; still, switching has to happen quickly once a threshold in the input signal is reached. Several computing al...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pcbi.1005100

Authors


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Department:
St Annes College
Hernansaiz-Ballesteros, RD More by this author
Dalchau, N More by this author
Csikász-Nagy, A More by this author

Contributors

Role:
Editor
Microsoft Research More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Computational Biology Journal website
Volume:
13
Issue:
1
Pages:
e1005100
Publication date:
2017-01-05
Acceptance date:
2016-08-09
DOI:
EISSN:
1553-7358
ISSN:
1553-734X
Pubs id:
pubs:671081
URN:
uri:d20f87a9-7dfb-48a6-92f1-589105dd3996
UUID:
uuid:d20f87a9-7dfb-48a6-92f1-589105dd3996
Local pid:
pubs:671081

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