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Journal article

Somatic genetic changes accompanying lung tumor development.

Abstract:

Carcinomas are believed to develop by incremental steps of increasingly abnormal morphology driven by accumulating somatic genetic changes. This process is often difficult to study, as the early stages are undetectable. We used fluorescence bronchoscopy, which enhances detection of preinvasive bronchial lesions, and have obtained sequential biopsies of carcinoma in situ (CIS) from a patient with no detectable tumor and from a squamous cell carcinoma that developed 19 months after presentation...

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Publication status:
Published

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Publisher copy:
10.1002/gcc.20223

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Clinical Lab Sciences
Role:
Author
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Journal:
Genes, chromosomes and cancer
Volume:
44
Issue:
1
Pages:
65-75
Publication date:
2005-09-05
DOI:
EISSN:
1098-2264
ISSN:
1045-2257
URN:
uuid:d2020aa4-a7b7-4dc1-b365-74e26b3687c4
Source identifiers:
324046
Local pid:
pubs:324046

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