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Innate immune response to human bone marrow fibroblastic cell implantation in CB17 scid/beige mice.

Abstract:

Immunocompromised mouse models have been extensively used to assess human cell implantation for evaluation of cytotherapy, gene therapy and tissue engineering strategies, as these mice are deficient in T and B lymphoid cells. However, the innate immune response and its effect on human cell xenotransplantation in these mouse models are mainly unknown. The aim of this study is to characterise the myeloid populations in the spleen and blood of CB17 scid beige (CB17 sb) mice, and to study the inf...

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Publication status:
Published

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Publisher copy:
10.1002/jcb.20730

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
Role:
Author
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Journal:
Journal of cellular biochemistry
Volume:
98
Issue:
4
Pages:
966-980
Publication date:
2006-07-05
DOI:
EISSN:
1097-4644
ISSN:
0730-2312
URN:
uuid:d1f4f5d0-018d-4062-beaa-3b12599a259e
Source identifiers:
24884
Local pid:
pubs:24884

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