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Journal article

Measuring and using light in the melanopsin age

Abstract:
Light is a potent stimulus for regulating circadian, hormonal, and behavioral systems. In addition, light therapy is effective for certain affective disorders, sleep problems, and circadian rhythm disruption. These biological and behavioral effects of light are influenced by a distinct photoreceptor in the eye, melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs), in addition to conventional rods and cones. We summarize the neurophysiology of this newly described sensory pathway and consider implications for the measurement, production, and application of light. A new light-measurement strategy taking account of the complex photoreceptive inputs to these non-visual responses is proposed for use by researchers, and simple suggestions for artificial/architectural lighting are provided for regulatory authorities, lighting manufacturers, designers, and engineers.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.tins.2013.10.004

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author


Publisher:
Cell Press
Journal:
Trends in Neurosciences More from this journal
Volume:
37
Issue:
1
Pages:
1-9
Publication date:
2013-11-25
DOI:
EISSN:
1878-108X
ISSN:
0166-2236


Keywords:
Pubs id:
pubs:446477
UUID:
uuid:d1ea7566-21b5-4f53-8e71-2303fef3e25a
Local pid:
pubs:446477
Source identifiers:
446477
Deposit date:
2014-05-13

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