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mFISH analysis of chromosome aberrations induced in vitro by α-particle radiation: examination of dose-response relationships.

Abstract:

A multicolored FISH (mFISH) technique was used to characterize the cytogenetic damage associated with exposure to α-particle radiation with particular emphasis on the quality and quantity that is likely to be transmitted through cell division to descendant cells. Peripheral blood lymphocytes were irradiated in vitro with (238)Pu α particles with a range of mean doses up to 936 mGy and were cultured for 47 h. The dose responses for total aberrant cells, stable and unstable cells, and cells wit...

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Publication status:
Published

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Publisher copy:
10.1667/rr3020.1.2

Authors


Curwen, GB More by this author
Cadwell, KK More by this author
Thompson, J More by this author
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Journal:
Radiation research
Volume:
178
Issue:
5
Pages:
414-424
Publication date:
2012-11-05
DOI:
EISSN:
1938-5404
ISSN:
0033-7587
URN:
uuid:d1b43ce9-f7b7-4f1f-bfed-2c19ef788dab
Source identifiers:
364432
Local pid:
pubs:364432

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