Journal article icon

Journal article

Modulation of T cell activation by stomatin-like protein 2.

Abstract:

T cell activation through the Ag receptor (TCR) requires sustained signaling from signalosomes within lipid raft microdomains in the plasma membrane. In a proteomic analysis of lipid rafts from human T cells, we identified stomatin-like protein (SLP)-2 as a candidate molecule involved in T cell activation through the Ag receptor. In this study, we show that SLP-2 expression in human primary lymphocytes is up-regulated following in vivo and ex vivo activation. In activated T cells, SLP-2 inter...

Expand abstract

Actions


Access Document


Publisher copy:
10.4049/jimmunol.181.3.1927

Authors


Expand authors...
Journal:
Journal of immunology (Baltimore, Md. : 1950)
Volume:
181
Issue:
3
Pages:
1927-1936
Publication date:
2008-08-05
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:d1945643-4cbc-4588-8058-3646fd4d0591
Source identifiers:
426312
Local pid:
pubs:426312

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP