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Journal article

Effect of antihypertensive deprescribing on hospitalisation and mortality: long-term follow-up of the OPTiMISE randomised controlled trial

Abstract:

Background: Deprescribing of antihypertensive medications is recommended for some older patients with low blood pressure and frailty. The OPTiMISE trial showed that this deprescribing can be achieved with no differences in blood pressure control at 3 months compared with usual care. We aimed to examine effects of deprescribing on longer-term hospitalisation and mortality.

Methods: This randomised controlled trial enrolled participants...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1016/s2666-7568(24)00131-4

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
ORCID:
0000-0002-4461-8756
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
ORCID:
0000-0001-5360-9993

Contributors

Role:
Contributor


More from this funder
Funder identifier:
https://ror.org/029chgv08
Grant:
211182/Z/18/Z
More from this funder
Funder identifier:
https://ror.org/02wdwnk04
Grant:
PG/21/10341


Publisher:
Elsevier
Journal:
Lancet Healthy Longevity More from this journal
Volume:
5
Issue:
8
Pages:
e563-e573
Publication date:
2024-07-30
Acceptance date:
2024-06-24
DOI:
EISSN:
2666-7568
Pmid:
39094592


Language:
English
Keywords:
Pubs id:
2019474
Local pid:
pubs:2019474
Deposit date:
2024-10-22

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