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Strategies for autism candidate gene analysis.

Abstract:

The identification of autism susceptibility genes has moved a step closer over the last four years with the completion of eight whole genome screens for linkage. Several overlapping areas of linkage have been reported, most notably on chromosomes 7q22-31 and 2q32. These regions of replicated linkage provide a focus to search for candidate genes whose normal functions in neurodevelopment are altered to increase the risk for autism. Strategies that aim to narrow further the rather broad size of...

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Journal:
Novartis Foundation symposium
Volume:
251
Pages:
48-297
Publication date:
2003
EISSN:
1935-4657
ISSN:
1528-2511
URN:
uuid:d12a562f-3a5a-40f6-85ba-3e1b61684632
Source identifiers:
32506
Local pid:
pubs:32506

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