Journal article
Studies on the reaction of glutathione and formaldehyde using NMR.
- Abstract:
-
Within cells it is proposed that a major mechanism for the metabolism of formaldehyde is via its reaction with glutathione (GSH) to form S-hydroxymethylglutathione (HMG), which undergoes subsequent oxidation. In addition to HMG and the previously reported (5R,10S)-5-(carboxymethylcarbamoyl)-7-oxo-3-thia-1,6-diazabicyclo[4.4.1]undecane-10-carboxylic acid (BiGF(2)), NMR studies on the reaction of GSH with formaldehyde reveal two previously unassigned monocyclic structures. The results imply tha...
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- Publication status:
- Published
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- Publisher copy:
- 10.1039/c0ob00208a
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Bibliographic Details
- Journal:
- Organic and biomolecular chemistry
- Volume:
- 8
- Issue:
- 21
- Pages:
- 4915-4920
- Publication date:
- 2010-11-01
- DOI:
- EISSN:
-
1477-0539
- ISSN:
-
1477-0520
- Source identifiers:
-
67496
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:67496
- UUID:
-
uuid:d123714c-4616-446b-8cff-fc288e5c6b27
- Local pid:
- pubs:67496
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2010
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