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Brain-derived neurotrophic factor is an endogenous modulator of nociceptive responses in the spinal cord.

Abstract:

The primary sensory neurons that respond to noxious stimulation and project to the spinal cord are known to fall into two distinct groups: one sensitive to nerve growth factor and the other sensitive to glial cell-line-derived neurotrophic factor. There is currently considerable interest in the ways in which these factors may regulate nociceptor properties. Recently, however, it has emerged that another trophic factor-brain-derived neurotrophic factor (BDNF)-may play an important neuromodulat...

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Publisher copy:
10.1073/pnas.96.14.7714

Authors


Publisher:
National Academy of Sciences
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
96
Issue:
14
Pages:
7714-7718
Publication date:
1999-07-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:d11b4cc2-656a-4ee7-a53c-98ad3a3f6ee8
Source identifiers:
365804
Local pid:
pubs:365804

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