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Journal article

Local and remote immune-mediated inflammation after mild peripheral nerve compression in rats.

Abstract:

After experimental nerve injuries that extensively disrupt axons, such as chronic constriction injury, immune cells invade the nerve, related dorsal root ganglia (DRGs), and spinal cord, leading to hyperexcitability, raised sensitivity, and pain. Entrapment neuropathies, such as carpal tunnel syndrome, involve minimal axon damage, but patients often report widespread symptoms. To understand the underlying pathology, a tube was placed around the sciatic nerve in 8-week-old rats, leading to pro...

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Publication status:
Published

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Journal:
Journal of neuropathology and experimental neurology
Volume:
72
Issue:
7
Pages:
662-680
Publication date:
2013-07-05
DOI:
EISSN:
1554-6578
ISSN:
0022-3069
URN:
uuid:d119dae3-a03b-4dc2-a75a-fb78b136c655
Source identifiers:
470844
Local pid:
pubs:470844

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