Journal article
Using phenotypic heterogeneity to increase the power of genome-wide association studies: application to age at onset of ischaemic stroke subphenotypes.
- Abstract:
-
Genome-wide association studies (GWAS) have been successful in identifying common variants related to complex disorders. However, some disorders have proved resistant to this strategy with few associations confirmed, despite evidence from twin and family studies of a genetic component. Sophisticated strategies that account for phenotypic heterogeneity may be required to uncover these genetic contributions. Age at onset is an example of a potential source of this heterogeneity in ischaemic str...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/gepi.21729
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Bibliographic Details
- Journal:
- Genetic epidemiology
- Volume:
- 37
- Issue:
- 5
- Pages:
- 495-503
- Publication date:
- 2013-07-01
- DOI:
- EISSN:
-
1098-2272
- ISSN:
-
0741-0395
- Source identifiers:
-
406191
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:406191
- UUID:
-
uuid:d1195b2a-77a5-4598-8262-c9557e742820
- Local pid:
- pubs:406191
- Deposit date:
- 2013-11-17
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- Copyright date:
- 2013
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