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A Plasmodium falciparum strain expressing GFP throughout the parasite's life-cycle.

Abstract:

The human malaria parasite Plasmodium falciparum is responsible for the majority of malaria-related deaths. Tools allowing the study of the basic biology of P. falciparum throughout the life cycle are critical to the development of new strategies to target the parasite within both human and mosquito hosts. We here present 3D7HT-GFP, a strain of P. falciparum constitutively expressing the Green Fluorescent Protein (GFP) throughout the life cycle, which has retained its capacity to complete spo...

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Publisher copy:
10.1371/journal.pone.0009156

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
Wellcome Trust More from this funder
Biotechnology and Biological Sciences Research Council More from this funder
EU BioMalPar Network of Excellence More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
5
Issue:
2
Article number:
e9156
Publication date:
2010-01-01
DOI:
EISSN:
1932-6203
Language:
English
Keywords:
UUID:
uuid:d105e39f-3445-4808-b60a-e2d7ccc6bcf1
Local pid:
pubs:262826
Source identifiers:
262826
Deposit date:
2013-02-20

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