Journal article icon

Journal article

A fast and highly sensitive blood culture PCR method for clinical detection of Salmonella enterica serovar Typhi.

Abstract:

BACKGROUND: Salmonella Typhi causes an estimated 21 million new cases of typhoid fever and 216,000 deaths every year. Blood culture is currently the gold standard for diagnosis of typhoid fever, but it is time-consuming and takes several days for isolation and identification of causative organisms. It is then too late to initiate proper antibiotic therapy. Serological tests have very low sensitivity and specificity, and no practical value in endemic areas. As early diagnosis of the disease a...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1186/1476-0711-9-14

Authors


More by this author
Institution:
University of Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Paediatrics, Biomedical Research Centre
Role:
Author
More from this funder
Funding agency for:
Pollard, AJ
National Institute for Health Research Biomedical Research Centre Programme More from this funder
Publisher:
BioMed Central Ltd. Publisher's website
Journal:
Annals of Clinical Microbiology and Antimicrobials Journal website
Volume:
9
Issue:
1
Pages:
Article: 14
Publication date:
2010-01-01
DOI:
EISSN:
1476-0711
ISSN:
1476-0711
URN:
uuid:d103eb16-c60d-485a-bd3e-808db1a19725
Source identifiers:
119375
Local pid:
pubs:119375

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP