Journal article
MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine
- Abstract:
-
The cell envelope of Mycobacterium tuberculosis is notable for the abundance of mycolic acids (MAs), essential to mycobacterial viability, and of other species-specific lipids. The mycobacterial cell envelope is extremely hydrophobic, which contributes to virulence and antibiotic resistance. However, exactly how fatty acids and lipidic elements are transported across the cell envelope for cell-wall biosynthesis is unclear. Mycobacterial membrane protein Large 3...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
-
(Accepted manuscript, pdf, 68.2MB)
-
(Accepted manuscript, pdf, 13.6MB)
-
- Publisher copy:
- 10.1073/pnas.1901346116
Authors
Bibliographic Details
- Publisher:
- National Academy of Sciences Publisher's website
- Journal:
- Proceedings of the National Academy of Sciences of the United States of America Journal website
- Volume:
- 116
- Issue:
- 23
- Pages:
- 11241-11246
- Publication date:
- 2019-05-21
- Acceptance date:
- 2019-05-03
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
- Pmid:
-
31113875
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:1003112
- UUID:
-
uuid:d0f926b0-5026-40bb-972e-288295c04e12
- Local pid:
- pubs:1003112
- Source identifiers:
-
1003112
- Deposit date:
- 2019-07-02
Terms of use
- Copyright holder:
- PNAS
- Copyright date:
- 2019
- Notes:
- © 2019 Published under the PNAS license. This is the accepted manuscript version of the article. The final version is available online from National Academy of Sciences at: https://doi.org/10.1073/pnas.1901346116
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