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Utilisation of triacylglycerol and non-esterified fatty acid by the working rat heart: myocardial lipid substrate preference.

Abstract:

Utilisation and subsequent metabolic fate (oxidation; tissue lipid deposition) of non-esterified fatty acid (NEFA), very-low-density lipoprotein-triacylglycerol (VLDL-TAG), and chylomicron-triacylglycerol (CM-TAG) alone or in combination by isolated working rat heart were examined. Cardiac mechanical function was maintained regardless of lipid substrate used. NEFA and CM-TAG were assimilated to a greater extent than VLDL-TAG; CM-TAG utilisation (76+/-10 nmol fatty acid/min per g wet wt.; n=8)...

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Authors


Bennett, MJ More by this author
Journal:
Biochimica et biophysica acta
Volume:
1533
Issue:
2
Pages:
99-109
Publication date:
2001-09-05
DOI:
ISSN:
0006-3002
URN:
uuid:d0eccc34-c9fa-4473-8c02-cdce38714d94
Source identifiers:
238079
Local pid:
pubs:238079

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