Journal article
Campath-1G in vivo confers a low incidence of graft-versus-host disease associated with a high incidence of mixed chimaerism after bone marrow transplantation for severe aplastic anaemia using HLA-identical sibling donors.
- Abstract:
-
We have evaluated the effect of in vivo Campath-1G on engraftment and GVHD in 23 patients with severe aplastic anaemia transplanted from HLA-identical sibling donors. In 14 patients Campath 1g was given pre-transplant for up to 9 days in an attempt to overcome graft rejection (group 1). In nine patients Campath-1G was given pre-transplant, but also continued post-transplant until day +5 to reduce GVHD (group 2). There were three patients with late graft failure in group I following initial ne...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Bone marrow transplantation
- Volume:
- 17
- Issue:
- 5
- Pages:
- 819-824
- Publication date:
- 1996-05-05
- EISSN:
-
1476-5365
- ISSN:
-
0268-3369
- URN:
-
uuid:d0dcd509-19bd-42e1-b76e-fcd82d4f32cf
- Source identifiers:
-
1860
- Local pid:
- pubs:1860
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 1996
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