- Abstract:
-
Atheromatous plaques contain various cell types, including macrophages, endothelial cells and smooth-muscle cells. To investigate the possible interactions between secreted matrix metalloproteinases and high-density lipoprotein (HDL) components, we tested the above cell types by culturing them for 24 h. HDL3 (HDL subfractions with average sizes of between 8.44 nm for HDL3A and 7.62 nm for HDL3C) were then incubated in their cell-free conditioned media. Proteolytic degradation of apolipoprotei...
Expand abstract - Publisher copy:
- 10.1042/0264-6021:3620627
-
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- Journal:
- Biochemical Journal
- Volume:
- 362
- Issue:
- 3
- Pages:
- 627-634
- Publication date:
- 2002-03-15
- DOI:
- ISSN:
-
0264-6021
- URN:
-
uuid:d0dcb397-9e85-4dd2-b856-f2d5a6b260c8
- Source identifiers:
-
231071
- Local pid:
- pubs:231071
- Language:
- English
- Keywords:
- Copyright date:
- 2002
Journal article
Macrophage metalloproteinases degrade high-density-lipoprotein-associated apolipoprotein A-I at both the N- and C-termini
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