Journal article
Characterization of subpopulations of chicken mononuclear phagocytes that express TIM4 and CSF1R
- Abstract:
-
The phosphatidylserine receptor TIM4, encoded by TIMD4, mediates the phagocytic uptake of apoptotic cells. We applied anti-chicken TIM4 mAbs in combination with CSF1R reporter transgenes to dissect the function of TIM4 in the chick (Gallus gallus). During development in ovo, TIM4 was present on the large majority of macrophages, but expression became more heterogeneous posthatch. Blood monocytes expressed KUL01, class II MHC, and CSF1R-mApple uniformly. Around 50% of monocytes were positive f...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
+ Biotechnology and Biological Sciences Research Council
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Grant:
BBS/E/D/10002071
Bibliographic Details
- Publisher:
- American Society of Immunologists Publisher's website
- Journal:
- Journal of Immunology Journal website
- Volume:
- 202
- Issue:
- 4
- Pages:
- 1186-1199
- Publication date:
- 2019-01-09
- Acceptance date:
- 2018-12-03
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- Pmid:
-
30626692
Item Description
- Language:
- English
- Pubs id:
-
pubs:959959
- UUID:
-
uuid:d0d796da-8d46-40e5-a4de-c5f632519f0a
- Local pid:
- pubs:959959
- Source identifiers:
-
959959
- Deposit date:
- 2019-02-28
Terms of use
- Copyright holder:
- American Association of Immunologists
- Copyright date:
- 2019
- Notes:
- © 2019 by The American Association of Immunologists, Inc.
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