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HIV-exposed uninfected children: a growing population with a vulnerable immune system?

Abstract:

Through the successful implementation of policies to prevent mother-to-child-transmission (PMTCT) of HIV-1 infection, children born to HIV-1-infected mothers are now much less likely to acquire HIV-1 infection than previously. Nevertheless, HIV-1-exposed uninfected (HEU) children have substantially increased morbidity and mortality compared with children born to uninfected mothers (unexposed uninfected, UU), predominantly from infectious causes. Moreover, a range of phenotypical and functiona...

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Publication status:
Published

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Publisher copy:
10.1111/cei.12251

Authors


Garcia Knight, M More by this author
Heyderman, RS More by this author
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Journal:
Clinical and experimental immunology
Volume:
176
Issue:
1
Pages:
11-22
Publication date:
2014-04-05
DOI:
EISSN:
1365-2249
ISSN:
0009-9104
URN:
uuid:d0c9dffe-d7b9-4f87-88cf-d642982b0b5f
Source identifiers:
441780
Local pid:
pubs:441780

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