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Mechanistic roles of autophagy in hematopoietic differentiation

Abstract:

Autophagy is increasingly recognized for its active role in development and differentiation. In particular, its role in the differentiation of hematopoietic cells has been extensively studied, likely because blood cells are accessible, easy to identify and purify and their progenitor tree is well defined. This review aims to discuss the mechanisms by which autophagy impacts on differentiation, using hematopoietic cell types as examples. Autophagy’s roles include the remodeling during terminal...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/febs.13962

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
More from this funder
Funding agency for:
Riffelmacher, T
Grant:
PhD prize studentship
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Funding agency for:
Simon, A
Grant:
Investigator
Publisher:
Wiley Publisher's website
Journal:
FEBS Journal Journal website
Volume:
284
Issue:
7
Pages:
1008–1020
Publication date:
2016-11-01
Acceptance date:
2016-11-09
DOI:
EISSN:
1742-4658
ISSN:
1742-464X
Source identifiers:
657868
Keywords:
Pubs id:
pubs:657868
UUID:
uuid:d0b86ff6-8aa2-4f0c-b559-57739ada52a5
Local pid:
pubs:657868
Deposit date:
2016-11-15

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