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Mechanistic roles of autophagy in hematopoietic differentiation

Abstract:

Autophagy is increasingly recognized for its active role in development and differentiation. In particular, its role in the differentiation of hematopoietic cells has been extensively studied, likely because blood cells are accessible, easy to identify and purify and their progenitor tree is well defined. This review aims to discuss the mechanisms by which autophagy impacts on differentiation, using hematopoietic cell types as examples. Autophagy’s roles include the remodeling during terminal...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1111/febs.13962

Authors


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Department:
Oxford, MSD, NDORMS, KIR
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Department:
Oxford, MSD, NDORMS, KIR
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Funding agency for:
Riffelmacher, T
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Funding agency for:
Simon, A-K
Publisher:
Wiley Publisher's website
Journal:
FEBS Journal Journal website
Volume:
284
Issue:
7
Pages:
1008–1020
Publication date:
2016-11-05
Acceptance date:
2016-11-09
DOI:
EISSN:
1742-4658
ISSN:
1742-464X
Pubs id:
pubs:657868
URN:
uri:d0b86ff6-8aa2-4f0c-b559-57739ada52a5
UUID:
uuid:d0b86ff6-8aa2-4f0c-b559-57739ada52a5
Local pid:
pubs:657868

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