Thesis
Characterization of endoplasmic reticulum targeting liposomes as drug delivery vesicles
- Abstract:
-
Due to rapid viral and drug resistance mutations, there is a great need for broad-spectrum antiviral therapies that target the host rather than viral processes. This research builds upon previous studies developing α-glucosidase inhibitors known as iminosugars as broad-spectrum antiviral drugs. Initially pH-sensitive liposomes were designed and developed as drug delivery vehicles to enhance cellular internalization for α-glucosidase inhibitors for HIV-1 antiviral treatment. Recent studies ...
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Funding
Bibliographic Details
- Publication date:
- 2012
- Type of award:
- MSc by Research
- Level of award:
- Masters
- URN:
-
uuid:d0b095d7-5a90-4660-8c3c-e36b51fbe436
- Local pid:
- ora:11556
Item Description
- Language:
- English
- Keywords:
- Subjects:
Terms of use
- Copyright holder:
- Kelly Skelton
- Copyright date:
- 2012
- Notes:
- This thesis is not currently available on ORA.
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