Thesis
Studying protein-DNA interactions in vitro and in vivo using single-molecule photoswitching
- Abstract:
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Protein-DNA interactions govern the fundamental cellular processes of DNA replication, transcription, repair, and chromosome organisation. Despite their importance, the detailed molecular mechanisms of protein-DNA interactions and their organisation in the cell remain elusive. The complexity of molecular biology demands new experimental concepts that resolve the structural and functional diversity of biomolecules.
In this thesis, I describe fluorescence methods that give a direct vi...
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(Dissemination version, pdf, 28.8MB)
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Bibliographic Details
- Publication date:
- 2013
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- UUID:
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uuid:d0a52864-6d26-44a4-8fb7-5d12624a04ba
- Local pid:
- ora:7225
Item Description
- Language:
- English
- Keywords:
- Subjects:
Terms of use
- Copyright holder:
- Uphoff, S
- Copyright date:
- 2013
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