Journal article icon

Journal article

Effects of iron supplementation and depletion on hypoxic pulmonary hypertension: two randomized controlled trials.

Abstract:

CONTEXT: Hypoxia is a major cause of pulmonary hypertension in respiratory disease and at high altitude. Recent work has established that the effect of hypoxia on pulmonary arterial pressure may depend on iron status, possibly acting through the transcription factor hypoxia-inducible factor, but the pathophysiological and clinical importance of this interaction is unknown. OBJECTIVE: To determine whether increasing or decreasing iron availability modifies altitude-induced hypoxic pulmonary hy...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1001/jama.2009.1404

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Expand authors...
Journal:
JAMA
Volume:
302
Issue:
13
Pages:
1444-1450
Publication date:
2009-10-01
DOI:
EISSN:
1538-3598
ISSN:
0098-7484
Source identifiers:
74007
Language:
English
Keywords:
Pubs id:
pubs:74007
UUID:
uuid:d0980837-4c54-4c5d-b19d-9d37c7af475c
Local pid:
pubs:74007
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP