- Abstract:
-
We have used MR segmented inversion recovery ratio imaging (SIRRIM) of the substantia nigra pars compacta to detect and correlate nigral signal change in idiopathic Parkinson's disease (PD) and parkin patients with striatal (18)F-dopa uptake. Nine PD patients, nine parkin patients, and eight control subjects were studied with a combination of MR inversion recovery sequences sensitive to nigral cell loss. Blinded independent observer rating and quantified nigral signal analysis were performed ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/mds.20702
-
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- Journal:
- Movement disorders : official journal of the Movement Disorder Society
- Volume:
- 21
- Issue:
- 3
- Pages:
- 299-305
- Publication date:
- 2006-03-05
- DOI:
- EISSN:
-
1531-8257
- ISSN:
-
0885-3185
- URN:
-
uuid:d08ee6aa-9d63-4d20-bdda-73320cb93958
- Source identifiers:
-
308525
- Local pid:
- pubs:308525
- Language:
- English
- Keywords:
- Copyright date:
- 2006
Journal article
Nigral degeneration and striatal dopaminergic dysfunction in idiopathic and Parkin-linked Parkinson's disease.
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