Journal article
Independence of HIF1a and androgen signaling pathways in prostate cancer
- Abstract:
-
Background: Therapeutic targeting of the androgen signaling pathway is a mainstay treatment for prostate cancer. Although initially effective, resistance to androgen targeted therapies develops followed by disease progression to castrate-resistant prostate cancer (CRPC). Hypoxia and HIF1a have been implicated in the development of resistance to androgen targeted therapies and progression to CRCP. The interplay between the androgen and hypoxia/HIF1a signaling axes was inve... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
National Institute for Health Research
More from this funder
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- BMC Cancer Journal website
- Volume:
- 20
- Issue:
- 1
- Article number:
- 469
- Publication date:
- 2020-05-25
- Acceptance date:
- 2020-04-22
- DOI:
- EISSN:
-
1471-2407
- Pmid:
-
32450824
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1107266
- Local pid:
- pubs:1107266
- Deposit date:
- 2020-05-30
Terms of use
- Copyright holder:
- Tran et al.
- Copyright date:
- 2020
- Rights statement:
- © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record