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Journal article

Multilayered Defense in HLA-B51-Associated HIV Viral Control

Abstract:

Polymorphism in the HLA region of a chromosome is the major source of host genetic variability in HIV-1 outcome, but there is limited understanding of the mechanisms underlying the beneficial effect of protective class I alleles such as HLA-B57, -B27, and -B51. Taking advantage of a unique cohort infected with clade B' HIV-1 through contaminated blood, in which many variables such as the length of infection, the infecting viral strain, and host genetic background are controlled, we performed ...

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Publication status:
Published

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Publisher copy:
10.4049/jimmunol.1100316

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Journal:
JOURNAL OF IMMUNOLOGY
Volume:
187
Issue:
2
Pages:
684-691
Publication date:
2011-07-15
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:d07d057d-be8a-4faf-ad1c-d3c8fab72120
Source identifiers:
166576
Local pid:
pubs:166576
Language:
English

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