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Thesis

Cognitive function in multiple sclerosis and its modulation by cholinergic drugs

Abstract:

In order to assess cognitive function in multiple sclerosis (MS) and the effect of cholinergic modulation, experiments were conducted using functional magnetic resonance imaging (fMRI) to assess the brain activation during cognitive tasks.

A study comparing the processing of verbal working memory with an N-back task found that patients showed smaller increase in activation than healthy controls with greater task difficulty, suggesting a reduced functional reserve. Controls and pati...

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Institution:
University of Oxford
Division:
MSD
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Publication date:
2005
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Subjects:
UUID:
uuid:d07ad815-4fc6-43b7-96dc-97a2705d6c6a
Local pid:
td:603851722
Source identifiers:
603851722
Deposit date:
2014-07-22

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